Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug, JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 국제전문학술지(SCI급), 7명(공동제1저자), JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, TAYLOR & FRANCIS LTD

Discovery of benzodioxane analogues as lead candidates of AIMP2-DX2 inhibitors, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 국제전문학술지(SCI급), 5명(공동제1저자), BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD

AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis, NATURE COMMUNICATIONS, 국제전문학술지(SCI급), 21명(공동제1저자), NATURE COMMUNICATIONS, NATURE PORTFOLIO

Allosteric Inhibition of the Tumor-Promoting Interaction Between Exon 2-Depleted Splice Variant of Aminoacyl-Transfer RNA Synthetase-Interacting Multifunctional Protein 2 and Heat Shock Protein 70((S)), JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 국제전문학술지(SCI급), 12명(공동제1저자), JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS

An Isoform of the Oncogenic Splice Variant AIMP2-DX2 Detected by a Novel Monoclonal Antibody, BIOMOLECULES, 국제전문학술지(SCI급), 12명(공동제1저자), BIOMOLECULES, MDPI

Anticancer Activity of Pyrimethamine via Ubiquitin Mediated Degradation of AIMP2-DX2, MOLECULES, 국제전문학술지(SCI급), 6명(공동제1저자), MOLECULES, MDPI

Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy, JOURNAL OF MEDICINAL CHEMISTRY, 국제전문학술지(SCI급), 14명(공동제1저자), JOURNAL OF MEDICINAL CHEMISTRY, AMER CHEMICAL SOC

2-Aminophenylpyrimidines as Novel Inhibitors of Aminoacyl-tRNA Synthetase Interacting Multifunctional Protein 2 (AIMP2)-DX2 for Lung Cancer Treatment, JOURNAL OF MEDICINAL CHEMISTRY, 국제전문학술지(SCI급), 8명(공동참여저자), JOURNAL OF MEDICINAL CHEMISTRY, AMER CHEMICAL SOC

Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development, NATURE CHEMICAL BIOLOGY, 국제전문학술지(SCI급), 17명(공동참여저자), NATURE CHEMICAL BIOLOGY, NATURE PUBLISHING GROUP

ERK-dependent phosphorylation of the linker and substrate-binding domain of HSP70 increases folding activity and cell proliferation, EXPERIMENTAL AND MOLECULAR MEDICINE, 국제전문학술지(SCI급), 3명(공동참여저자), EXPERIMENTAL AND MOLECULAR MEDICINE, NATURE PUBLISHING GROUP

Purification and biophysical characterization of the AIMP2-DX2 protein, PROTEIN EXPRESSION AND PURIFICATION, 국제전문학술지(SCI급), 7명(공동참여저자), PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS INC ELSEVIER SCIENCE

Data on optimization of expression and purification of AIMP2-DX2 protein in Escherichia coli, DATA IN BRIEF, 국제전문학술지(SCI급), 7명(공동참여저자), DATA IN BRIEF, ACADEMIC PRESS INC ELSEVIER SCIENCE

Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2, CANCER RESEARCH, 국제전문학술지(SCI급), 1명(단독 제1저자), CANCER RESEARCH, AMER ASSOC CANCER RESEARCH

Suppression of lysyl-tRNA synthetase, KRS, causes incomplete epithelial-mesenchymal transition and ineffective cell-extracellular matrix adhesion for migration, INTERNATIONAL JOURNAL OF ONCOLOGY, 국제전문학술지(SCI급), 9명(공동참여저자), INTERNATIONAL JOURNAL OF ONCOLOGY, SPANDIDOS PUBL LTD

PharmDB-K: Integrated Bio-Pharmacological Network Database for Traditional Korean Medicine, PLOS ONE, 국제전문학술지(SCI급), 15명(공동참여저자), PLOS ONE, PUBLIC LIBRARY SCIENCE

Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels, ONCOTARGET, 국제전문학술지(SCI급), 19명(공동참여저자), ONCOTARGET, IMPACT JOURNALS LLC

Promiscuous methionyl-tRNA synthetase mediates adaptive mistranslation to protect cells against oxidative stress, JOURNAL OF CELL SCIENCE, 국제전문학술지(SCI급), 15명(공동참여저자), JOURNAL OF CELL SCIENCE, COMPANY BIOLOGISTS LTD

Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction, NATURE CHEMICAL BIOLOGY, 국제전문학술지(SCI급), 35명(공동제1저자), NATURE CHEMICAL BIOLOGY, NATURE PUBLISHING GROUP

Characterization of the interaction between lysyl-tRNA synthetase and laminin receptor by NMR, FEBS LETTERS, 국제전문학술지(SCI급), 9명(공동참여저자), FEBS LETTERS, ELSEVIER SCIENCE BV

Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 국제전문학술지(SCI급), 10명(공동참여저자), PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, WILEY-LISS

Chemical suppression of an oncogenic splicing variant of AIMP2 induces tumour regression, BIOCHEMICAL JOURNAL, 국제전문학술지(SCI급), 13명(공동제1저자), BIOCHEMICAL JOURNAL, PORTLAND PRESS LTD

Interaction of two translational components, lysyl-tRNA synthetase and p40/37LRP, in plasma membrane promotes laminin-dependent cell migration, FASEB JOURNAL, 국제전문학술지(SCI급), 11명(공동제1저자), FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL

Splicing variant of AIMP2 as an effective target against chemoresistant ovarian cancer, JOURNAL OF MOLECULAR CELL BIOLOGY, 국제전문학술지(SCI급), 11명(공동참여저자), JOURNAL OF MOLECULAR CELL BIOLOGY, OXFORD UNIV PRESS

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug, BMC SYSTEMS BIOLOGY, 국제전문학술지(SCI급), 13명(공동참여저자), BMC SYSTEMS BIOLOGY, BIOMED CENTRAL LTD

CDA: Combinatorial Drug Discovery Using Transcriptional Response Modules, PLOS ONE, 국제전문학술지(SCI급), 10명(공동참여저자), PLOS ONE, PUBLIC LIBRARY SCIENCE

Identification of CD23 as a functional receptor for the proinflammatory cytokine AIMP1/p43, JOURNAL OF CELL SCIENCE, 국제전문학술지(SCI급), 7명(공동참여저자), JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD

Cancer-Associated Splicing Variant of Tumor Suppressor AIMP2/p38: Pathological Implication in Tumorigenesis, PLOS GENETICS, 국제전문학술지(SCI급), 21명(공동참여저자), PLOS GENETICS, PUBLIC LIBRARY SCIENCE

Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice, AGING CELL, 국제전문학술지(SCI급), 8명(공동참여저자), AGING CELL, BLACKWELL PUBLISHING

AIMP2 promotes TNFα-dependent apoptosis via ubiquitin-mediated degradation of TRAF2, Journal of Cell Science, 국제전문학술지(SCI급), 8명(공동참여저자), Journal of Cell Science, The Company of Biologists Ltd.